![]() Furthermore, we analyzed the expression of cell cycle regulators and components of the extracellular matrix in the stromal cells. We analyzed the expression of cell cycle regulators, including c-Myc, cyclin D1, p21(Cip1), p27(Kip1), Ki-67, and p16(INK4a), in the epithelial cells of patients with fibrocystic disease, ductal carcinoma in situ, and normal breast tissue. We hypothesized that the development of fibrocystic disease is related to alterations in the proliferation rate of epithelial and stromal cells. This item can be shipped worldwide.Dysregulation of cell cycle regulators and extracellular matrix components in breast epithelial and stromal cells of patients with fibrocystic disease.įibrocystic disease is a heterogeneous disorder characterized by the development of fibrous and cystic breast lesions, which can progress to breast cancer. The seller is “chrisbusser” and is located in Sidney, New South Wales. This item is in the category “Cars, Vans
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